Which of the following administration routes for drugs is more significantly affected by first-pass metabolism?

Principles Of Pharmacology Coursework

Which of the following administration routes for drugs is more significantly affected by first-pass metabolism?
Oral
Sublingual
Intravenous
Rectal
Intramuscular

Which one of the following is CORRECT?
The compound is an inhibitor of adenylate cyclase enzyme
The compound is a competitive antagonist of muscarinic receptor
The compound is a non-competitive antagonist of muscarinic receptors
The compound is an agonist of muscarinic receptor
The compound is a non-competitive antagonist of nicotine receptor

 

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