Medical Microbiology
Discuss considerations around sample quality and transport and how it affects laboratory results. Discuss the tests performed by the laboratory on a urine sample, how test results confirm a diagnosis of urinary tract infection and provide an example of an automated technology currently in use in diagnostic laboratories.
The patient was a 58-year-old man who was seen in the HIV clinic for the evaluation of a new rash. He was taking antiretroviral therapy and had an undetectable HIV viral load and a normal CD4 count of 631cells/ml. Two months before the evaluation the man had had anonymous unprotected sex with another man. Treponema pallidium was made.
QUESTIONS
a) What is the pathogenesis of the disease, which this organism causes in human hosts?
What is the role of virulence factors or virulence associated proteins in this disease?