Explain a mechanism involved in the constitutive activation of a cellular pathway implicated in tumourigenesis.

Cancer and therapeutics

There are multiple risk factors associated with cancer. Provide four examples of risk factor and describe the transformation process of a healthy cell into a tumour cell.

Explain the role of tumour suppressor genes. In your answer provide a named example and identify which hallmark of cancer its dysregulation is involved in.

Describe the process of tissue invasion and metastasis.

Explain a mechanism involved in the constitutive activation of a cellular pathway implicated in tumourigenesis.

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